Prasterone is a synthetic hormone equivalent to biological dehydroepiandrosterone (DHEA, also called the hormone of youth), which is 80% produced by the adrenal gland and 20% by the ovary. The prasterone has an advantage: it acts only locally, inside the cells. Upon insertion into the vagina, it is activated by estrogen and testosterone for an increase in the number of superficial and intermediate cells and a reduction in the number of parabasal cells in the vaginal mucosa. In addition, a decrease in vaginal pH is observed which facilitates the growth of normal bacterial flora. Once the work is done, these hormones are inactivated within the vaginal cell itself, with a process called "intracrinology" discovered by Professor Fernand Labrie.